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How to Auto-Build a B2B Lead List with Claude & Clay

Writer: Anne Thompson
Anne Thompson
5 hours ago
2 min read

Building a high-converting B2B outreach list usually means spending hours jumping between LinkedIn, email finders, and messy spreadsheets. If your team is manually copy-pasting lead details, you are burning valuable sales hours on low-value data entry.


In this edition of the Learning Lab, we break down how to pair Claude AI with data-enrichment tool Clay to instantly find targeted B2B prospects, find verified work emails, and draft personalized outreach—all on autopilot.


Watch the complete workflow in the video below, and follow along with our quick-start blueprint.



Step 1: Define Your Ideal Customer Profile (ICP) in Claude

Instead of starting with a massive, unrefined contact database, use Claude to sharpen your target criteria first.


  • Open Claude and input your core product or service.

  • The Playbook: Ask Claude: "Act as a B2B revenue strategist. List the top 3 job titles, company sizes, and specific operational pain points for businesses that need [your offer]."

  • The Result: Claude provides exact search parameters (e.g., Head of Operations at 20–50 person logistics firms) so you don't waste budget pulling irrelevant leads.


Step 2: Push Search Parameters into Clay

Clay acts as an aggregator that connects over 50+ data providers (including LinkedIn, Clearbit, and Apollo) into one single workspace.


  • Open a new workspace table in Clay and select Find Companies/People.

  • Paste the exact job titles and firmographic parameters provided by Claude into the search filters.

  • Clay will populate your table with hundreds of verified leads in seconds.


Step 3: Auto-Enrich & Verify Contact Info

Having a list of names is useless if the emails bounce.


  • Add a Waterfall Enrichment column in Clay.

  • Clay will automatically search multiple databases sequentially to find and double-check work email addresses and direct dial phone numbers.

  • Non-valid or dead emails are automatically filtered out before you ever pay for the data.


Step 4: Draft Hyper-Personalized First Lines with Claude

Now for the secret sauce: using AI to write a unique, zero-fluff introductory sentence for every single contact on your list.


  • Connect Claude directly inside your Clay table using the internal integration feature.

  • The Prompt: Command Claude to read each lead's recent news, job title, or company description and draft a single, specific 1-sentence opening line.

  • Example: "Saw that [Company] recently opened a new regional distribution hub in Dallas—congrats on the expansion."


Step 5: Export Straight to Your Dialing or Email Tool

With clean emails, verified phone numbers, and personalized icebreakers in place, your list is fully cooked.


  • Click Export to push the enriched list directly into your CRM (HubSpot, Salesforce) or your automated outbound campaign tool (CallHub, Smartlead).

  • Your reps can jump straight into high-converting conversations without spending a single minute on manual data entry.

The ROI Check: What previously took a sales development representative (SDR) 10 to 12 hours of manual research and spreadsheet formatting can now be completely executed in under 15 minutes.

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